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碳酸氢钠与枸橼酸在片剂中作为崩解剂的主要崩解机理为()

发布日期:2023-04-30

碳酸氢钠与枸橼酸在片剂中作为崩解剂的主要崩解机理为()
A

毛细管作用

B

改善了药物的润湿性

C

酶解作用

D

膨胀作用

E

产气作用

试题解析

崩解剂

崩解剂是指能使片剂在胃肠液中迅速裂碎成细小颗粒的物质,从而使功能成分迅速溶解吸收,发挥作用。这类物质大都具有良好的吸水性和膨胀性,从而实现片剂的崩解。除了缓释片以及某些特殊用途的片剂以外,一般的片剂中都应加有崩解剂。

中文名
崩解剂
崩解机理
毛细管作用
特性
良好的
定义
能使片剂在胃肠液中迅速裂碎成细小颗粒的物质
过程
润湿、虹吸、破碎
常见示例
干淀粉、羧甲基淀粉钠

片剂

片剂是药物与辅料均匀混合后压制而成的片状或异形片状的固体制剂。片剂以口服普通片为主,也有含片、舌下片、口腔贴片、咀嚼片、分散片、泡腾片、阴道片、速释或缓释或控释片与肠溶片等。

中文名
片剂
组成
药物与辅料均匀混合后压制而成
发展历史
由药丸发展起来
外文名
tablet
使用方式
以口服为主
特点
质量稳定等

机理

机理是指为实现某一特定功能,一定的系统结构中各要素的内在工作方式以及诸要素在一定环境条件下相互联系、相互作用的运行规则和原理。对机理有两种解释:一是机理指为实现某一特定功能,一定的系统结构中各要素的内在工作方式以及诸要素在一定环境下相互联系、相互作用的运行规则和原理;二是指事物变化的理由和道理,从机理的概念分析,机理包括形成要素和形成要素之间的关系两个方面。化学动力学中,“机理”是指从原子的结合关系中来描绘化学过程。如果其过程是动力学控制的,机理是指原子水平的表面过程。

中文名
机理
两种解释
机理指为实现某一特定功能
学科
化学
外文名
mechanism
描绘
化学过程

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此试题出现在

主管中药师专业实践能力

中药药剂学

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